Simon Barak Caine, PhD

Associate Professor of Psychology, Harvard Medical School
In high school and college, Simon Barak Caine worked in four research laboratories. He collected his first data that would be published at the age of 16, on brain mechanisms for discriminating between various visual stimuli in laboratory turtles and pigeons. After completing his bachelor's degree in biological basis of behavior, he became a PhD student in the laboratory of George F. Koob at the Scripps Research Institute in La Jolla, a world leader in the neurobiology of addiction and the current director of the National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health. The first Caine and Koob research report was published in Science, and the most recent publication by Caine (2017) in the Journal of Pharmacology and Experimental Therapeutics was on the same topic, a persistency by design. Caine's two most influential findings were published in his two favorite journals, the Journal of Pharmacology and Experimental Therapeutics and the Journal of Neuroscience, the latter being voted a "Must Read" by the Faculty of 1000 peer review committee. Both articles demonstrated, via complementary approaches, that the abuse potential of cocaine is dependent upon its increasing dopamine in brain synapses. Caine's self-reported most important contribution is to teaching and mentoring.


  • PhD University of California, San Diego