Simon Barak Caine, PhD

Associate Professor of Psychology, Harvard Medical School
In high school and college, Barak Caine worked in four research laboratories. He collected his first data, published at the age of sixteen, on brain mechanisms for discriminating between various visual stimuli in laboratory turtles and pigeons. After completing his bachelor's degree in Biological Basis of Behavior, he became a PhD student in the laboratory of George F. Koob, Director of the National Institute on Alcoholism and Alcohol Abuse, at the Scripps Research Institute in La Jolla, a world leader in the neurobiology of addiction. The first Caine and Koob research report was published in Science, and the most recent publication by Caine (2017) in JPET (Journal of Pharmacology and Experimental Therapeutics) was on the same topic. Caine's two most influential findings were published in JPET and the Journal of Neuroscience, the latter being voted a "Must Read" by the "Faculty of 1000" peer review committee. Both articles demonstrated, via complementary approaches, that the abuse potential of cocaine is dependent upon its increasing dopamine in brain synapses.


  • PhD University of California, San Diego